Trifluoromethylation in organic chemistry describes any organic reaction that introduces a trifluoromethyl group in an organic compound. Trifluoromethylated compounds are of some importance in pharma and agrochemicals. Several notable pharmaceutical compounds have a trifluoromethyl group incorporated: fluoxetine,mefloquine, Leflunomide, nulitamide, dutasteride, bicalutamide, aprepitant, celecoxib, fipronil, fluazinam, penthiopyrad, picoxystrobin, fluridone, norflurazon, sorafeniband triflurazin. A relevant agrochemical is trifluralin
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