Chemical biology is a scientific discipline spanning the fields of chemistry, biology, and physics. It involves the application of chemical techniques, tools, and analyses, and often compounds produced through synthetic chemistry, to the study and manipulation of biological systems. Chemical biologists attempt to use chemical principles to modulate systems to either investigate the underlying biology or create new function. Research done by chemical biologists is often closer related to that of cell biology than biochemistry. Biochemists study of the chemistry of biomolecules and regulation of biochemical pathways within cells and tissues, e.g. cAMP or cGMP, while chemical biologists deal with novel chemical compounds applied to biology.
- △Systems of interest
- ▽Proteomics
- ◇Glycobiology
- ◇Combinatorial chemistry
- ◇Molecular sensing
- ▽siRNA-A tool in chemical biology
- ◇Employing biology
- ◇Protein misfolding and aggregation as a cause of disease
- ◇Chemical synthesis of peptides
- ◇Protein design by directed evolution
- ▽Biocompatible click cycloaddition reactions in chemical biology
- ◇Discovery of biomolecules through metagenomics
- ◇Protein phosphorylation
- ▽Metal complexes in medicine
- ▽Synthetic biology
- ◇Chemical approaches to stem-cell biology
- ▽Fluorescence for assessing protein location and function
- ◇Applications of DNA microarrays in chemical biology
- ▽Applications of Chemical Biology in Drug Discovery
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