Monday, May 16, 2016

The Abramov and Pudovik reactions - wiki

The Abramov and Pudovik reactions are the related conversions of trialkyl and dialkyl phosphites (respectively) to α-hydroxy phosphonates in the presence of carbonyl compounds. Both reactions proceed by similar mechanisms involving the attack of the nucleophilic phosphorus atom on the carbonyl carbon.They are named after Russian chemists Vasily Abramov (1904–1968) and Arkady Pudovik (1916–2006).
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